Compartment cover, kit and method for forming the same

ABSTRACT

A vial pack cover, a vial pack kit, and a method for forming the vial pack cover is provided. The vial pack cover can simultaneously cover a plurality of containers while preventing the contents of the containers from degrading or permeating through the cover. In addition, the vial pack cover allows a user to access individual containers without having to remove the cover from the un-accessed containers. The vial pack cover generally includes: (1) a plurality of plug portions joined together and formed from a heat curable rubber; and (2) a barrier layer covering each of the plug portions.

BACKGROUND OF THE INVENTION

1. Technical Field

The present invention generally relates to a vial pack cover, a vialpack kit, and a method for forming the same. More particularly, thepresent invention relates to a vial pack cover and method for formingthe same for engaging a vial pack having a plurality of containerstherein.

2. Background Art

In the medical, analytical chemistry, and biotechnology field, vialpacks are often used for simultaneously testing multiple reactions. Suchvial packs often include a plurality of compartments into which vials orother similar vessels are placed. Materials or samples are inserted intothe removable vials, or in some instances, directly into thecompartments of the vial pack. Accordingly, a cover or microplate isrequired for the vial pack so that the samples contained therein willnot be spilled or otherwise released to the surrounding environment,contiguous containers, or become contaminated with outside agents.Heretofore, many have attempted to solve this problem by employinginferior variations. Examples include the following, all of which areherein incorporated by reference:

U.S. Pat. No. 2,698,272 to Clapp et al.;

U.S. Pat. No. 2,884,150 to Weichselbaum et al.;

U.S. Pat. No. 3,302,854 to Midgley et al.;

U.S. Pat. No. 3,744,661 to Fischer, Jr.;

U.S. Pat. No. 5,112,574 to Horton;

U.S. Pat. No. 5,282,543 to Picozza et al.; and

U.S. Pat. No. 5,324,482 to Scaramella et al.

All of these related art devices are inadequate because they fail toprovide, inter alia, a barrier layer on a cover. The failure to providea barrier layer can result in the degredation of the cover from solventsor other material placed within the containers. Moreover, a barrierlayer prevents gasses accumulated within the containers from permeatingthrough the cover and into the surrounding environment.

In addition, none of the related art references disclose a cover thatallows a user to simultaneously cover a plurality of containers whilestill allowing the user to access an individual container without havingto remove the cover from the entire vial pack. Accordingly, with theserelated devices, a user must remove the cover from all of the containersto access one individual container. Such a requirement may lead tospillage of the samples contained therein or contamination by outsideagents. Therefore, there exists the need for a vial pack cover andmethod for forming the same that will allow a user to simultaneouslycover a plurality containers without concern for the cover beingdegraded or permeated therethrough by the contents of the containers. Inaddition, there exists a need for the cover to be such that a user mayaccess individual containers without having to remove the cover from theun-accessed containers.

SUMMARY OF THE INVENTION

The present invention overcomes the deficiencies of the related art byincluding a vial pack cover and method for forming the same that willallow a user to simultaneously cover a plurality of containers whilepreventing the contents held therein from degrading the cover,permeating through the cover, or contaminating other containers. Inaddition, the vial pack cover of the present invention is such that auser may access individual containers while allowing the cover to remainon the un-accessed containers.

According to one aspect of the present invention, a method for forming acoated vial pack cover is provided, which includes: (1) providing abarrier layer on a mold having a plurality of cavities therein; (2)providing an amount of heat curable rubber to the mold; (3) forming avial pack cover, including a plurality of plug portions coated with thebarrier layer; and 4) removing the vial pack cover from the mold.

According to a second aspect of the present invention, a method of usinga coated heat curable rubber as a cover for a vial pack is provided. Themethod includes: (1) providing a heat curable rubber cover including aplurality of plug portions, wherein the plug portions are coated with abarrier layer; and (2) engaging the cover with a vial pack having aplurality of containers therein, wherein each plug portion releasablyengages one of the containers

According to a third aspect of the present invention, a vial pack coveris provided. The vial pack cover includes: (1) a plurality of plugportions joined together, wherein the plug portions are formed from aheat curable rubber; and (2) a barrier layer covering each of the plugportions.

According to a fourth aspect of the present invention, a vial pack coveris provided and includes: (1) a support sheet; (2) a plurality of plugportions fixed to the support sheet, wherein both the support sheet andthe plug portions are formed from heat curable rubber; and (3) a barrierlayer, wherein the barrier layer coats each of the plug portions.

According to a fifth aspect of the present invention, a vial pack kit isprovided. The vial pack kit includes: (1) a pack, wherein the packincludes a plurality of containers; and (2) a cover for covering thepack, wherein the cover includes: (a) a support sheet; (b) a pluralityof plug portions integrally formed as a part of the support sheet,wherein both the support sheet and the plug portions are formed from aheat curable rubber; and (c) a barrier layer coating each of the plugportions, wherein each plug portion releasably engages one of thecontainers of the pack.

According to a sixth aspect of the present invention, a vial pack kit isprovided. The vial pack kit includes: (1) a device for covering a vialpack including a plurality of plug portions formed from a heat curablerubber, wherein the plug portions are joined together; and (2) anapparatus for removing one of the plug portions from the device.

It is therefore an advantage of the present invention to provide a vialpack cover for simultaneously covering a plurality of containers whilepreventing the contents of the containers from degrading or permeatingthrough the cover. In addition, it is also an advantage of the presentinvention to provide a cover that will allow a user to access individualcontainers without having to remove the cover from the un-accessedcontainers.

The invention resides not in any one of these features per se, butrather in the particular combination of all of them herein disclosed andclaimed. Those skilled in the art will appreciate that the conception,upon which this disclosure is based, may readily be utilized as a basisfor the designing of other structures, methods and systems for carryingout the several purposes of the present invention. Further, the abstractis neither intended to define the invention of the application, which ismeasured by the claims, nor is it intended to be limiting as to thescope of the invention in any way.

BRIEF DESCRIPTION OF THE DRAWINGS

These and other features and advantages of this invention will be morereadily understood from the following detailed description of thevarious aspects of the preferred embodiments of the invention taken inconjunction with the accompanying drawings in which:

FIG. 1 is a flow chart of a method for forming a coated vial pack coverin accordance with an embodiment of the present invention;

FIG. 2 is a flow chart of a method of using a coated heat curable rubberas a cover for a vial pack in accordance with an embodiment of thepresent invention;

FIG. 3 is a front sectional view of a heat curable rubber and a mold inaccordance with an embodiment of the present invention;

FIG. 4 is a top view of a vial pack in accordance with an embodiment ofthe present invention;

FIG. 5 is a top view of a vial pack cover in accordance with anembodiment of the present invention;

FIG. 6 is a partial side view of the vial pack cover prior to engagingthe vial pack in accordance with an embodiment of the present invention;and

FIG. 7 is a front view of a cutter from one embodiment of the presentinvention for removing one portion of the vial pack cover.

It is noted that the drawings of the invention are not to scale. Thedrawings are merely schematic representations, not intended to portrayspecific parameters of the invention. The drawings are intended todepict only typical embodiments of the invention, and therefore shouldnot be considered as limiting the scope of the invention. In thedrawings, like numbering represents like elements between the drawings.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

Referring now to the drawings, FIGS. 1-7 show the vial pack cover andmethod for forming the same in accordance with the present invention.FIG. 1, depicts a flowchart of a method 10 for forming a vial pack cover36. The first step 12 of the method 10 is to provide a barrier layer 50on a mold having a plurality of cavities 27 therein. The mold is shownin FIG. 3 and includes body portion 26, depressions 27, and cap 22having finger-like projections 23 thereon. Although a precise number ofdepressions is not necessary, many vial packs 28 are formed withspecific number compartments. Thus, the mold used to form the vial packcover 36 should include an equal quantity of depressions. In addition,although, the barrier layer 50 is shown as being applied only to thebody portion 26 of the mold, it should be understood that the barrierlayer 50 may be applied to additional components of the mold dependingon the needs of the user and the product that is desired.

Barrier layer 50 is preferably polytetrafluoroethylene (PTFE), howeverit should be understood that many equivalents exist. For example, anymaterial that will protect an elastomer from solvents, such as toluene,acetone, or the like and that will slow down or prevent the permeationof gasses will suffice, such as aluminum. In addition, barrier layer 50is preferably applied to the base portion 26 of the mold by spraying.However, it should be understood that other application techniques canbe used. For example, barrier layer 50 could be applied as a solid, drypre-formed sheet that takes the form of the base portion 26, includingthe depressions 27.

The next step 14 in the method 10 is to provide an amount of heatcurable rubber 24 to the mold. The heat curable rubber is the materialthat will form the vial pack cover 36 after the method 10 is complete.Preferably the heat curable rubber is silicone rubber, however it shouldbe appreciated that many equivalents may be used. For example, the heatcurable rubber 24 can be any silicone elastomer, organic elastomer,viton, sanoprene, or EPDM. In addition, the heat curable rubber 24 ispreferably provided to the mold in a 21″×4″ segment weighingapproximately 24 grams. However, it should be understood that thequantity of the heat curable rubber 24 that is provided to the mold willvary with the size and dimensions of the mold.

It should also be appreciated that the barrier layer 50 can be appliedor sprayed directly onto the heat curable rubber 24 prior to itsinsertion into the mold. This can be in addition to in or lieu of theapplication of the barrier layer 50 to the mold.

The next step 16 of the method 10 is to form a vial pack cover 36 thatincludes a plurality of plug portions 48. This is generally accomplishedby a compression molding. Specifically heat and pressure are applied tothe mold to cure the heat curable rubber into a vial pack cover 36having a plurality of plug portions 48, each of which are coated withthe barrier layer 50. The heat and pressure applied to the mold arepreferably about 340 F. and about 500 PSI, respectively. However, itshould be understood that the operating conditions may vary. Inaddition, although compression molding is preferred, it should beappreciated that other processes may be used. For example, a liquidinjection molding (LIM) process or a room temperature vulcanizing (RTV)process could be implemented.

Finally, the last step 17 of the method 10 is to remove the completedvial pack cover 36 from the mold. FIGS. 5 and 6 show the vial pack cover36 constructed in accordance this method 10. Referring to these Figs.,the vial pack cover 36 generally includes a support sheet 42, a topsurface 44 of plug portion 48, needle aperture 40, optional ribbing 38and 46, and a barrier layer 50 covering the plug portions 48. Theribbing 38 is optional and can be used to join the plug portions 48together and to increase the overall durability and strength of the vialpack cover 36. In addition, as indicated above, the barrier layer ispreferably applied only to the base portion 26 of the mold. Accordingly,only the bottom surface of the support sheet 42 and the plug portions 48are shown as having been covered with the barrier layer 50. However, ifthe user had applied the barrier layer to additional components of themold, it should be understood that additional locations of the vial packcover 36 would also be covered by the barrier layer 50 in additionallocations.

The vial pack cover 36 is used to engage a vial pack 28 or other similarcontainer. As shown in FIGS. 4 and 6 the vial pack 28 includes a bodyportion 52, an upper surface 30, and compartments 34. As indicatedabove, a precise quantity of compartments 34 is not necessary, however,it should also be understood that the quantity of compartments 34 shouldbe matched by the quantity of plug portions 48. In addition, the vialpack 28 should be constructed of a material that will not be degraded bythe contents placed therein, as known by those of ordinary skill in theart.

Inside of the compartments 34, vials 32 or other similar storage vesselsmay optionally be placed. A user can insert the materials to be testedinside of the vials 32 or into the compartments 34 directly. It shouldbe understood that the term containers as set forth herein refers toeither the compartments or the vials.

Once the materials have been inserted into the compartments, the userwill then engage the vial pack cover 36 with the vial pack 28, and inthe event vials 32 are used, with the vials 32 as well. Optionally, thevial pack 28 may include a ridge or groove 54. In such an embodiment,the ribbing 46, optionally disposed along the periphery of the supportsheet 42 of the vial pack cover 36, will engage the ridge 54 to aid inretaining the vial pack cover 36 to the vial pack 28. It should beunderstood, however, that many equivalent variations exist for furthersecuring the vial pack cover 36 to the vial pack 28. For example, aclamp(s) (not shown), complementary male and female connectors (notshown), snap connectors (not shown), or various adhesives (not shown)could be used.

Once the vial pack cover 36 is secured over the vial pack 28, the plugportions 48 will protrude into the openings of compartments 34 and, ifused, the openings of the vials 32 as well. The plug portions 48 areformed to releasably engage the compartments 34 or, if used, the vials32. In particular, the frictional force between the plug portions 48 andthe compartments 34 or the vials 32 will ensure that the vial pack cover36 remains secured thereto such that material contained within thecompartments 34 or vials 32 will remain therein.

The purpose of the barrier layer 50 is to ensure that the vial packcover 36, and more specifically the plug portions 48, do not becomedegraded or damaged by the materials placed within the compartments 34or the vials 32. In addition, barrier layer 50 will slow down or preventthe permeation of gasses from inside of the compartments 34 or vials 32to the outside environment. In related devices that lack the barrierlayer 50, not only are increased instances of cover degradation observedbut also increased permeation of gasses through the cover 36. Gaspermeation through the vial pack cover 36 leads to contamination of thesurrounding environment as well as the degraded accuracy of the medical,chemical, or biotechnological test(s) being performed due to loss of thesample.

As indicated above, silicone rubber is preferred as the material fromwhich the vial pack cover 36 is formed because of its variouscharacteristics. Specifically, silicone rubber is able to maintain itsconsistency and characteristics from temperatures as low as about −165F. to as high as about 600 F. In addition, silicone rubber is clean whenpunctured inasmuch as a needle or syringe can penetrate the siliconewithout becoming contaminated with fragments of silicone. Moreover, oncepunctured by a needle or the like, silicone rubber is compliant and willre-seal.

Once the vial pack cover 36 is secured over the vial pack 38, a user mayperform testing or other operation on the contents of the compartments34 or vials 32 by injected materials through the needle apertures 40positioned on the top surface 44 of the plug portions 48. The needleapertures 40 do not extend completely through the plug portion 48. Incontrast, they extend only partially therethrough to ensure that thematerial contained within the compartments 34 or the vials 32 does notspill through the needle apertures 40. The needle apertures arepreferably formed during the molding of the vial pack cover 36 and areformed by the finger-like projections 23 disposed along the cap 22 ofthe mold. However, it should be appreciated that many variations existfor forming the needle apertures 40. For example, the needle apertures40 can be formed after the molding has been completed.

By injecting the desired material through the vial pack cover 36, a useris not forced to remove the cover from the vial pack 28. Thus, spillageof the materials contained within the compartments 34 or the vials 32 isnot risked. In addition, because the vial pack cover 36 is formed from asilicone or organic elastomer, it is easily and cleanly penetrable by aneedle or syringe and will re-seal upon the withdrawal of the needle.This will ensure that fragments of the vial pack cover 36 do not contactand/or contaminate the materials contained within the compartments 34 orthe vials 32. Moreover, by using an elastomer that is re-sealable, thehole made in the plug portion 48 by the needle will close once theneedle is withdrawn. Thus, reducing the risk of material spillage.

Referring to FIG. 7, a cutter 56 is shown and generally includes ahandle portion 58, a cutting portion 60, and a cutting edge 64. As shownthe cutter 56 can be used to remove individual plug portions 48 and/orvials 32 from the vial pack 28. This need arises when a user desires toaccess one of the compartments 34 or vials 32. Without a cutter, a usermust completely remove the entire vial pack cover 36 from the vial pack28 in order to access individual compartments 34 or vials 32. Such asrequisite often leads to spillage or contamination of the materialscontained therein. However, with the cutter 56 of the present a user canaccess individual compartments 34 or vials 32.

To be used, the cutter 56 is centered over the plug portion 48 of thecompartment 34 or vial 32 in which access is desired. The cutter 56 isthen moved in the direction indicated by directional arrow 62 whilebeing rotated about the plug portion 48. The cutting edge 64 will cutthrough the support sheet 42 and the ribbing 38, thus, freeing anindividual plug portion 48 from the vial pack cover 36. The user is thenleft with either an individual vial 32 that is plugged and free from thevial pack 28 or an individually uncovered compartment 34. However, thevial pack cover 36 remains firmly secured over the un-accessedcompartments 34 or vials 32. Although a specific design for the cutter56 has been described, it should be appreciated that many equivalentdevices could be implemented. Moreover, it is envisioned that otherapparatuses may be used for removing the plug portions 48. For example,the upper surface 44 of the plug portions 48 could be constructed withperforations or serrated edges allowing the user to manually removeindividual plug portions 48 from the cover 36.

FIG. 2 shows another method 18 in accordance with the present invention.Specifically, the method 18 is a method of using a coated heat curablerubber as a cover for a vial pack. The first step 20 of the method is toprovide a heat curable rubber including a plurality of plug portionscoated with a barrier layer. This structure represents the vial packcover 36 formed from the method 10 and is described above. The secondstep 21 is to engage the cover 36 with a vial pack 28 having a pluralityof containers therein. This indicates that each plug portion 48 of thevial pack cover 36 will releasably engage either a compartment 34 or, ifused, a vial 32, as described in detail above.

With respect to the first method 10, the following experiment run wasrecorded:

(1) the mold was preheated to 340 F.;

(2) preforms of silicone rubber of approximately 0.200″ in thicknesswere provided;

(3) the preforms were cut to 1½″ in width and 3″ in length and weighed24 grams;

(4) the bottom of the mold was sprayed with CAMIE 2000 TEFLON;

(5) the part were molded using 20 tons on the lab press and 3000 psi onthe lab extension press;

(6) the molding was performed using a 5 minute cycle time;

(7) the molded parts were removed from the mold and another preform(s)was inserted into the mold for the next cycle; and

(8) the cycle was repeated.

The foregoing description of the preferred embodiments of this inventionhas been presented for purposes of illustration and description. It isnot intended to be exhaustive or to limit the invention to the preciseform disclosed, and obviously, many modifications and variations arepossible. Such modifications and variations that may be apparent to aperson skilled in the art are intended to be included within the scopeof this invention as defined by the accompanying claims.

What is claimed is:
 1. A method, comprising the following steps:providing a heat curable rubber cover for an at least one compartment,said cover including a support sheet having a bottom surface and aplurality of plug portions thereon; covering the plug portions and thebottom surface of the support sheet with a non-rubber barrier layer,wherein there is no intervening layer of adhesive between the cover andthe barrier layer; and covering the at least one compartment with thecover therein, by fully engaging the cover with the at least onecompartment, wherein only the barrier layer of each plug portion and thebarrier layer of the support sheet releasably seals the at least onecompartment.
 2. The method of claim 1, wherein the step of providing thebarrier layer includes providing the barrier layer frompolytetrafluoroethylene.
 3. The method of claim 1, wherein the step ofproviding the heat curable rubber includes selecting the heat curablerubber from one of silicone rubber, silicone elastomer, organicelastomer, viton, sanoprene and EPDM.
 4. The method of claim 1, furthercomprising: injecting through the compartment cover with a needle;withdrawing the needle; and re-sealing the compartment cover.
 5. A coverfor a compartment, comprising: a plurality of plug portions joinedtogether to form a surface of the cover, wherein the plug portions areformed from a heat curable rubber; and a barrier layer formed directlyon and coextensively with said surface of the cover, wherein the barrierlayer covers said surface of the cover, wherein when the cover fullyengages the compartment only the barrier layer releasably seals thecompartment.
 6. The compartment cover of claim 5, wherein the heatcurable rubber is selected from the group consisting of silicone rubber,silicone elastomer, organic elastomer, viton, sanoprene and EPDM.
 7. Thecompartment cover of claim 5, wherein the plug portions are needlepenetrable.
 8. The compartment cover of claim 5, wherein the heatcurable rubber is re-sealable.
 9. The compartment cover of claim 5,wherein the barrier layer includes polytetrafluoroethylene.
 10. Acompartment cover comprising: a support sheet; a plurality of plugportions fixed to the support sheet, wherein both the support sheet andthe plug portions have a coextensive exposed surface and are formed froma heat curable rubber; and a barrier layer formed directly on thecoextensive exposed surface of the plug portions and the support sheet,wherein the coextensive exposed surface of the plug portions and thesurface of the support sheet is coated with the barrier layer, whereinwhen the cover fully engages a compartment only the barrier layerreleasably seals the compartment.
 11. The compartment cover of claim 10,wherein the heat curable rubber is selected from the group consisting ofsilicone rubber, silicone elastomer, organic elastomer, viton, sanopreneand EPDM.
 12. The compartment cover of claim 10, wherein the barrierlayer includes polytetrafluoroethylene.
 13. The compartment cover ofclaim 10, wherein the plug portions are needle penetrable.
 14. Thecompartment cover of claim 10, wherein the heat curable rubber isre-sealable.
 15. The compartment cover of claim 10, further comprisingribbing extending between the plug portions.
 16. The compartment coverof claim 15, wherein the ribbing also extends around the periphery of asupport sheet.
 17. A kit, comprising: a pack, wherein the pack includesa plurality of compartments open to a surface of the pack; a cover forcovering the pack, wherein the cover includes: a support sheet; aplurality of plug portions integrally formed as a part of the supportsheet, wherein both the support sheet and the plug portions have acoextensive exposed surface and are formed from a heat curable rubber;and a barrier layer formed directly on the coextensive exposed surfacesof both the support sheet and the plug portions, wherein when the coveris fully engaged with the pack, only the barrier layer releasably sealsat least one of said plurality of compartments of the pack.
 18. The kitof claim 17, wherein the heat curable rubber is selected from the groupconsisting of silicone rubber, silicone elastomer, organic elastomer,viton, sanoprene and EPDM.
 19. The kit of claim 17, wherein the barrierlayer includes polytetrafluoroethylene.
 20. The kit of claim 17, whereinthe plug portions are needle penetrable.
 21. The kit of claim 17,wherein the heat curable rubber is re-sealable.
 22. The kit of claim 17,wherein the compartments further comprise containers, and wherein thecontainers are placed into the openings of the pack.
 23. The kit ofclaim 22, wherein each plug portion releasably engages a vial.
 24. Thekit of claim 17, further comprising a device for removing individualplug portions from the kit.
 25. The kit of claim 24, wherein the deviceis a cutter.
 26. A kit comprising: a pack, wherein the pack includes aplurality of compartments open to a surface of the pack; a support sheetand a plurality of plug portions joined together, wherein the supportsheet and the plug portions have a coextensive exposed surface andwherein the sheet and the plurality of plug portions are formed from aheat curable rubber; a barrier layer formed directly on the coextensiveexposed surface of the support sheet and the plug portions, wherein thebarrier layer covers the exposed coextensive surface, and wherein whensaid support sheet and the plug portions fully engage the pack, only thebarrier layer releasably seals at least one of said plurality ofcompartments of the pack.
 27. The kit of claim 26, wherein the heatcurable rubber is selected from the group consisting of silicone rubber,silicone elastomer, organic elastomer, viton, sanoprene and EPDM. 28.The kit of claim 26, wherein the plug portions are needle penetrable.29. The kit of claim 28, wherein the needle penetrable plug portions arere-sealable.
 30. The kit of claim 26, wherein the barrier layer includespolytetrafluoroethylene.
 31. A compartment cover comprising: a pluralityof plug portions joined together to form a surface of the cover, whereinthe plug portions are formed from a heat curable rubber; and a barrierlayer formed directly and coextensively on said surface of the cover,wherein the barrier layer covers said surface of the cover, wherein whenthe cover fully engages a compartment only the barrier layer releasablyseals the compartment.
 32. A method of using a heat curable rubber as acover for a compartment, comprising the following steps: providing aheat curable rubber cover including a support sheet and a plurality ofplug portions, wherein the plug portions are coated with a barrier layerformed on a surface of each of the plug portions and the support sheetwithout an intervening adhesive layer; and fully engaging the cover witha compartment having a plurality of containers therein, wherein only thebarrier layer of each plug portion releasably seals each of thecontainers.
 33. A kit, comprising: a pack, wherein the pack includes aplurality of compartments open to a surface of the pack, thecompartments holding containers; a compartment cover formed from a heatcurable rubber, wherein the cover includes: a support sheet; and aplurality of plug portions integrally formed as a part of the supportsheet, wherein the support sheet has an exposed surface; and acoextensive barrier layer formed on the plug portions and the exposedsurface of the support sheet without an intervening adhesive layer,wherein when the cover is fully engaged with the pack, only the barrierlayer releasably at least seals one of the containers of the pack.
 34. Akit, comprising: a pack, wherein the pack includes a plurality ofcompartments open to a surface of the pack; a compartment cover formedfrom a heat curable rubber, wherein the cover includes: a plurality ofplug portions joined together to form an exposed surface; and acoextensive barrier layer formed on the plug portions and the exposedsurface of the support sheet, without an intervening adhesive layer,wherein when the cover is fully engaged with the pack, only the barrierlayer releasably seals at least one of the compartments of the pack, anda cutter for removing one of the plug portions from the compartment kit.35. A compartment cover, comprising: a plurality of plug portions joinedtogether to form an exposed surface, wherein the plug portions areformed from a heat curable rubber; and a polytetrafluoroethylene barrierlayer formed directly and coextensively on said surface, wherein thebarrier layer covers said surface of the cover, wherein when the coverfully engages a compartment only the barrier layer releasably seals thecompartment.
 36. The compartment cover of claim 35, wherein the heatcurable rubber is selected from the group consisting of silicone rubber,silicone elastomer, viton, sanoprene or EPDM.
 37. The compartment coverof claim 35, wherein a needle aperture is formed in at least one of theplug portions.
 38. The compartment cover of claim 35, wherein the heatcurable rubber is re-sealable.
 39. A kit, comprising: a pack, whereinthe pack includes a plurality of compartments open to a surface of thepack; a compartment cover formed from a heat curable rubber, wherein thecover includes: a plurality of plug portions joined together to form anexposed surface, wherein the plug portions are formed from a heatcurable rubber; a coextensive barrier layer formed directly on the plugportions and the exposed surface of the support sheet, wherein when thecover is fully engaged with the pack, only the barrier layer releasablyseals at least one of the compartments of the pack, and a needleaperture formed in at least one of the plug portions.
 40. A kit,comprising: a pack, wherein the pack includes a plurality ofcompartments open to a surface of the pack; a compartment cover formedfrom a heat curable rubber, wherein the cover includes: a plurality ofplug portions joined together to form an exposed surface, wherein theplug portions are formed from a heat curable rubber; and a coextensivepolytetrafluoroethylene barrier layer formed directly on the plugportions and the exposed surface of the support sheet, wherein when thecover is fully engaged with the pack, only the barrier layer releasablyseals at least one of the compartments of the pack.